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Immunological Markers in the Diagnosis and Prediction of Autoimmune Type 1a Diabetes

In Brief

Several autoantibodies are associated with autoimmune type 1 diabetes. Measurements of islet autoantibodies can assist in the diagnosis of autoimmune diabetes, and the detection of islet autoantibodies in nondiabetic individuals indicates a significantly increased risk for the subsequent development of type 1 diabetes. When preventive therapies for type 1 diabetes become available, islet autoantibody screening of the general pediatric population should be considered to identify at-risk individuals.

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