Clinical Diabetes 23:130-136, 2005
© American Diabetes Association ®, Inc., 2005
Weight Management Using Lifestyle Modification in the Prevention and Management of Type 2 Diabetes: Rationale and Strategies
The American Diabetes Association,
the North American Association for the Study of Obesity and
and the American Society for Clinical Nutrition
Reprinted with permission from
Diabetes
Care 27:2067
-2073, 2004[Free Full Text]
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Introduction
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The prevalence of diabetes in the U.S. continues to rise by epidemic
proportions. This increase parallels the rising rates of obesity and
overweight observed over the past
decade.1,2
Indeed, as BMI increases, the risk of developing type 2 diabetes increases in
a "dose-dependent"
manner.3,4
The prevalence of type 2 diabetes is 3-7 times higher in obese than in
normal-weight adults, and those with a BMI > 35 kg/m2 are 20
times more likely to develop diabetes than those with a BMI between 18.5 and
24.9
kg/m2.5,6
In addition, weight gain during adulthood is also directly correlated with an
increased risk of type 2
diabetes.3,7-9
Obesity also complicates the management of type 2 diabetes by increasing
insulin resistance and blood glucose
concentrations.10
It is an independent risk factor for dyslipidemia, hypertension, and
cardiovascular
disease6,11-14
and, thus, increases the risk of cardiovascular complications and
cardiovascular mortality in patients with type 2
diabetes.15
The purpose of this statement is to review the important role of weight
management in the prevention and management of type 2 diabetes and to describe
strategies for achieving and maintaining a healthy body weight through
lifestyle modification. The use of weight loss medications and bariatric
surgery in the management of obesity will not be discussed in this document.
Pharmacotherapy can be a useful adjunct to lifestyle modification in the
long-term management of obesity in selected
patients.16 Weight
loss medications may be considered for those with a BMI 30 or those with
a BMI 27 plus obesity-related comorbid conditions. Weight loss surgery
may be a therapeutic alternative for patients with a BMI 40 or a BMI
35 plus comorbid
conditions.16
Comprehensive review articles that discuss the use of weight loss medications
and surgery in the management of obesity have recently been
published.17-20
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Benefits of weight loss
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Weight loss is an important goal . . . [Full Text of this Article]
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Indications and goals for weight loss therapy
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Diet
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Physical activity
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Facilitating lifestyle change in an office practice
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Maintaining weight loss
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Summary
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Specific recommendations
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Copyright © 2005 by the American Diabetes Association.
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