DOI: 10.2337/diaclin.26.3.121 © 2008 by the American Diabetes Association
Bariatric Surgery Improves Glycemic Control
Dixon JB, Obrien PE, Playfair J, Chapman L, Schachter LM, Skinner S, Proietto J, Bailey M, Anderson M: Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. JAMA 299:316 -323, 2008
Design. A randomized controlled trial comparing a conventional lifestyle change intervention to conventional management plus laparoscopic adjustable gastric banding for the outcomes of "diabetes regression," defined as fasting glucose < 126 mg/dl and hemoglobin A1c (A1C) < 6.2% while using no glucose-controlling medications. Subjects. Sixty patients with a BMI of 30-40 kg/m2 and recently (within 2 years) diagnosed diabetes.
Methods. Eligible participants were 20-60 years of age, had type 2
diabetes diagnosed within 2 years, and had no evidence of impaired renal
function or diabetic retinopathy. Potential participants completed a 3-month
run-in period that included efforts to optimize their diabetes treatment.
Those completing the run-in period were randomized, and no attempt was made to
blind patients or providers to their intervention
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