Integrated Physiology-Central Nervous System Regulation of Metabolism

Integrated Physiology-Central Nervous System Regulation of Metabolism

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Preproglucagon Neurons in the Nucleus of the Solitary Tract are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food
Marie K Holt, James E Richards, Daniel R Cook, Daniel I Brierley, Diana L Williams, Frank Reimann, Fiona M Gribble, Stefan Trapp

Diabetes Sep 2018, db180729; DOI: 10.2337/db18-0729
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Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects
Chelsea L. Faber, Miles E. Matsen, Kevin R. Velasco, Vincent Damian, Bao Anh Phan, Daniel Adam, Anthony Therattil, Michael W. Schwartz, Gregory J. Morton

Diabetes Dec 2018, 67 (12) 2518-2529; DOI: 10.2337/db18-0380
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Defining the Transcriptional Targets of Leptin Reveals a Role for Atf3 in Leptin Action
Margaret B. Allison, Warren Pan, Alexander MacKenzie, Christa Patterson, Kimi Shah, Tammy Barnes, Wenwen Cheng, Alan Rupp, David P. Olson, Martin G. Myers

Diabetes Jun 2018, 67 (6) 1093-1104; DOI: 10.2337/db17-1395
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Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus
Thomas A. Lutz, Bernd Coester, Lynda Whiting, Ambrose A. Dunn-Meynell, Christina N. Boyle, Sebastien G. Bouret, Barry E. Levin, Christelle Le Foll

Diabetes May 2018, 67 (5) 805-817; DOI: 10.2337/db17-1347
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Leptin Replacement Reestablishes Brain Insulin Action in the Hypothalamus in Congenital Leptin Deficiency
Sabine Frank-Podlech, Julia von Schnurbein, Ralf Veit, Martin Heni, Jürgen Machann, Jaana M. Heinze, Stephanie Kullmann, Jaida Manzoor, Saqib Mahmood, Hans-Ulrich Häring, Hubert Preissl, Martin Wabitsch, Andreas Fritsche

Diabetes Care Apr 2018, 41 (4) 907-910; DOI: 10.2337/dc17-1867
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SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity
Yalan Deng, Yuzhong Xiao, Feixiang Yuan, Yaping Liu, Xiaoxue Jiang, Jiali Deng, Geza Fejes-Toth, Aniko Naray-Fejes-Toth, Shanghai Chen, Yan Chen, Hao Ying, Qiwei Zhai, Yousheng Shu, Feifan Guo

Diabetes Apr 2018, 67 (4) 569-580; DOI: 10.2337/db17-1069
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Dissociation Between Hormonal Counterregulatory Responses and Cerebral Glucose Metabolism During Hypoglycemia
John J. Lee, Nadia Khoury, Angela M. Shackleford, Suzanne Nelson, Hector Herrera, Jo Ann Antenor-Dorsey, Katherine Semenkovich, Joshua S. Shimony, William J. Powers, Philip E. Cryer, Ana María Arbeláez

Diabetes Dec 2017, 66 (12) 2964-2972; DOI: 10.2337/db17-0574
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Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity
Jung Dae Kim, Chitoku Toda, Cristina M. Ramírez, Carlos Fernández-Hernando, Sabrina Diano

Diabetes Aug 2017, 66 (8) 2102-2111; DOI: 10.2337/db16-1558
Open Access
Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues
Jennifer S. ten Kulve, Dick J. Veltman, Victor E.A. Gerdes, Liselotte van Bloemendaal, Frederik Barkhof, Carolyn F. Deacon, Jens J. Holst, Madeleine L. Drent, Michaela Diamant, Richard G. IJzerman

Diabetes Care Nov 2017, 40 (11) 1522-1529; DOI: 10.2337/dc16-2113
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Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity
Yuanqing Gao, Clarita Layritz, Beata Legutko, Thomas O. Eichmann, Elise Laperrousaz, Valentine S. Moullé, Celine Cruciani-Guglielmacci, Christophe Magnan, Serge Luquet, Stephen C. Woods, Robert H. Eckel, Chun-Xia Yi, Cristina Garcia-Caceres, Matthias H. Tschöp

Diabetes Oct 2017, 66 (10) 2555-2563; DOI: 10.2337/db16-1278

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