Integrated Physiology-Liver

Integrated Physiology-Liver

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Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis
Brian N. Finck

Diabetes Dec 2018, 67 (12) 2485-2493; DOI: 10.2337/dbi18-0024
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Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin
Isaac Asare-Bediako, Rebecca L. Paszkiewicz, Stella P. Kim, Orison O. Woolcott, Cathryn M. Kolka, Miguel A. Burch, Morvarid Kabir, Richard N. Bergman

Diabetes Aug 2018, 67 (8) 1495-1503; DOI: 10.2337/db17-1520
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Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis
Béatrice Romier, Corinne Ivaldi, Hervé Sartelet, Andrea Heinz, Christian E.H. Schmelzer, Roselyne Garnotel, Alexandre Guillot, Jessica Jonquet, Eric Bertin, Jean-Louis Guéant, Jean-Marc Alberto, Jean-Pierre Bronowicki, Johanne Amoyel, Thinhinane Hocine, Laurent Duca, Pascal Maurice, Amar Bennasroune, Laurent Martiny, Laurent Debelle, Vincent Durlach, Sébastien Blaise

Diabetes Aug 2018, 67 (8) 1604-1615; DOI: 10.2337/db17-0490
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Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents
Teayoun Kim, Cassie L. Holleman, Shelly Nason, Deanna M. Arble, Nickki Ottaway, Joseph Chabenne, Christine Loyd, Jeong-a Kim, Darleen Sandoval, Daniel J. Drucker, Richard DiMarchi, Diego Perez-Tilve, Kirk M. Habegger

Diabetes Nov 2018, 67 (11) 2157-2166; DOI: 10.2337/db18-0068
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Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations—Role of Carbohydrate and Energy Availability
Kirstine N. Bojsen-Møller, Anne-Marie Lundsgaard, Sten Madsbad, Bente Kiens, Jens Juul Holst

Diabetes Nov 2018, 67 (11) 2129-2136; DOI: 10.2337/db18-0539
Open Access
SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis
X. Charlie Dong

Diabetes Jan 2018, 67 (1) 23-25; DOI: 10.2337/dbi17-0042
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PDK4 Deficiency Suppresses Hepatic Glucagon Signaling by Decreasing cAMP Levels
Bo-Yoon Park, Jae-Han Jeon, Younghoon Go, Hye Jin Ham, Jeong-Eun Kim, Eun Kyung Yoo, Woong Hee Kwon, Nam-Ho Jeoung, Yong Hyun Jeon, Seung-Hoi Koo, Byung-Gyu Kim, Ling He, Keun-Gyu Park, Robert A. Harris, In-Kyu Lee

Diabetes Oct 2018, 67 (10) 2054-2068; DOI: 10.2337/db17-1529
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Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
Teayoun Kim, Shelly Nason, Cassie Holleman, Mark Pepin, Landon Wilson, Taylor F. Berryhill, Adam R. Wende, Chad Steele, Martin E. Young, Stephen Barnes, Daniel J. Drucker, Brian Finan, Richard DiMarchi, Diego Perez-Tilve, Matthias Tschöp, Kirk M. Habegger

Diabetes Sep 2018, 67 (9) 1773-1782; DOI: 10.2337/db17-1502
Open Access
Response to Comment on Bril et al. Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients. Diabetes Care 2018;41:187–192
Fernando Bril, Kenneth Cusi

Diabetes Care Sep 2018, 41 (9) e137-e138; DOI: 10.2337/dci18-0026
Open Access
Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
Panu K. Luukkonen, Sanja Sädevirta, You Zhou, Brandon Kayser, Ashfaq Ali, Linda Ahonen, Susanna Lallukka, Véronique Pelloux, Melania Gaggini, Ching Jian, Antti Hakkarainen, Nina Lundbom, Helena Gylling, Anne Salonen, Matej Orešič, Tuulia Hyötyläinen, Marju Orho-Melander, Aila Rissanen, Amalia Gastaldelli, Karine Clément, Leanne Hodson, Hannele Yki-Järvinen

Diabetes Care Aug 2018, 41 (8) 1732-1739; DOI: 10.2337/dc18-0071

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