Islet Biology-Apoptosis

Islet Biology-Apoptosis

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The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival
Seyed Mojtaba Ghiasi, Nicolai Krogh, Björn Tyrberg, Thomas Mandrup-Poulsen

Diabetes Oct 2018, 67 (10) 2019-2037; DOI: 10.2337/db18-0073
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The Dysregulation of the DLK1-MEG3 Locus in Islets From Patients With Type 2 Diabetes Is Mimicked by Targeted Epimutation of Its Promoter With TALE-DNMT Constructs
Vasumathi Kameswaran, Maria L. Golson, Mireia Ramos-Rodríguez, Kristy Ou, Yue J. Wang, Jia Zhang, Lorenzo Pasquali, Klaus H. Kaestner

Diabetes Sep 2018, 67 (9) 1807-1815; DOI: 10.2337/db17-0682
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Doc2b Protects β-Cells Against Inflammatory Damage and Enhances Function
Arianne Aslamy, Eunjin Oh, Erika M. Olson, Jing Zhang, Miwon Ahn, Abu Saleh Md Moin, Ragadeepthi Tunduguru, Vishal A. Salunkhe, Rajakrishnan Veluthakal, Debbie C. Thurmond

Diabetes Jul 2018, 67 (7) 1332-1344; DOI: 10.2337/db17-1352
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Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide–Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells
Bryndon J. Oleson, Aaron Naatz, Sarah C. Proudfoot, Chay Teng Yeo, John A. Corbett

Diabetes May 2018, 67 (5) 898-910; DOI: 10.2337/db17-1062
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SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival
Jonàs Juan-Mateu, Maria Inês Alvelos, Jean-Valéry Turatsinze, Olatz Villate, Esther Lizarraga-Mollinedo, Fabio Arturo Grieco, Laura Marroquí, Marco Bugliani, Piero Marchetti, Décio L. Eizirik

Diabetes Mar 2018, 67 (3) 423-436; DOI: 10.2337/db17-0736
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Stress-Induced MicroRNA-708 Impairs β-Cell Function and Growth
Júlia Rodríguez-Comas, Alba Moreno-Asso, Juan Moreno-Vedia, Mercè Martín, Carlos Castaño, Anna Marzà-Florensa, Xavier Bofill-De Ros, Joan Mir-Coll, Joel Montané, Cristina Fillat, Rosa Gasa, Anna Novials, Joan-Marc Servitja

Diabetes Dec 2017, 66 (12) 3029-3040; DOI: 10.2337/db16-1569
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Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes
Marimar Hernandez-Perez, Gaurav Chopra, Jonathan Fine, Abass M. Conteh, Ryan M. Anderson, Amelia K. Linnemann, Chanelle Benjamin, Jennifer B. Nelson, Kara S. Benninger, Jerry L. Nadler, David J. Maloney, Sarah A. Tersey, Raghavendra G. Mirmira

Diabetes Nov 2017, 66 (11) 2875-2887; DOI: 10.2337/db17-0215
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GDF11 Attenuates Development of Type 2 Diabetes via Improvement of Islet β-Cell Function and Survival
Huan Li, Yixiang Li, Lingwei Xiang, JiaJia Zhang, Biao Zhu, Lin Xiang, Jing Dong, Min Liu, Guangda Xiang

Diabetes Jul 2017, 66 (7) 1914-1927; DOI: 10.2337/db17-0086
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Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation
Andrew T. Templin, Tanya Samarasekera, Daniel T. Meier, Meghan F. Hogan, Mahnaz Mellati, Michael T. Crow, Richard N. Kitsis, Sakeneh Zraika, Rebecca L. Hull, Steven E. Kahn

Diabetes Oct 2017, 66 (10) 2636-2645; DOI: 10.2337/db16-1352
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MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells
Kira Meyerovich, Natalia M. Violato, Makiko Fukaya, Violette Dirix, Nathalie Pachera, Lorella Marselli, Piero Marchetti, Andreas Strasser, Decio L. Eizirik, Alessandra K. Cardozo

Diabetes Sep 2017, 66 (9) 2446-2458; DOI: 10.2337/db16-1252

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