Islet Biology-Signal Transduction

Islet Biology-Signal Transduction

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Endogenous Fatty Acids Are Essential Signaling Factors of Pancreatic β-Cells and Insulin Secretion
Sebastian Hauke, Kaya Keutler, Prasad Phapale, Dmytro A. Yushchenko, Carsten Schultz

Diabetes Oct 2018, 67 (10) 1986-1998; DOI: 10.2337/db17-1215
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Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets
Rajakrishnan Veluthakal, Oleg G. Chepurny, Colin A. Leech, Frank Schwede, George G. Holz, Debbie C. Thurmond

Diabetes Oct 2018, 67 (10) 1999-2011; DOI: 10.2337/db17-1174
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Interleukin-6 Reduces β-Cell Oxidative Stress by Linking Autophagy With the Antioxidant Response
Michelle R. Marasco, Abass M. Conteh, Christopher A. Reissaus, John E. Cupit, Evan M. Appleman, Raghavendra G. Mirmira, Amelia K. Linnemann

Diabetes Aug 2018, 67 (8) 1576-1588; DOI: 10.2337/db17-1280
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Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca²⁺ Mobilization From Acidic Stores in Pancreatic α-Cells
Alexander Hamilton, Quan Zhang, Albert Salehi, Mara Willems, Jakob G. Knudsen, Anna K. Ringgaard, Caroline E. Chapman, Alejandro Gonzalez-Alvarez, Nicoletta C. Surdo, Manuela Zaccolo, Davide Basco, Paul R.V. Johnson, Reshma Ramracheya, Guy A. Rutter, Antony Galione, Patrik Rorsman, Andrei I. Tarasov

Diabetes Jun 2018, 67 (6) 1128-1139; DOI: 10.2337/db17-1102
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Regulation of K_ATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation
Shekhar Srivastava, Zhai Li, Irfana Soomro, Ying Sun, Jianhui Wang, Li Bao, William A. Coetzee, Charles A. Stanley, Chonghong Li, Edward Y. Skolnik

Diabetes May 2018, 67 (5) 849-860; DOI: 10.2337/db17-1433
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miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function
SeongHo Jo, Junqin Chen, Guanlan Xu, Truman B. Grayson, Lance A. Thielen, Anath Shalev

Diabetes Feb 2018, 67 (2) 256-264; DOI: 10.2337/db17-0506
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Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner
Lina Sakhneny, Eleonor Rachi, Alona Epshtein, Helen C. Guez, Shane Wald-Altman, Michal Lisnyansky, Laura Khalifa-Malka, Adina Hazan, Daria Baer, Avi Priel, Miguel Weil, Limor Landsman

Diabetes Mar 2018, 67 (3) 437-447; DOI: 10.2337/db17-0697
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A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic β-Cells
Teresa Buenaventura, Nisha Kanda, Phoebe C. Douzenis, Ben Jones, Stephen R. Bloom, Pauline Chabosseau, Ivan R. Corrêa, Domenico Bosco, Lorenzo Piemonti, Piero Marchetti, Paul R. Johnson, A.M. James Shapiro, Guy A. Rutter, Alejandra Tomas

Diabetes Mar 2018, 67 (3) 385-399; DOI: 10.2337/db17-0639
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MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells
Paul Richards, Latif Rachdi, Masaya Oshima, Piero Marchetti, Marco Bugliani, Mathieu Armanet, Catherine Postic, Sandra Guilmeau, Raphael Scharfmann

Diabetes Mar 2018, 67 (3) 461-472; DOI: 10.2337/db17-0595
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Hyperlipidemia-Induced MicroRNA-155-5p Improves β-Cell Function by Targeting Mafb
Mengyu Zhu, Yuanyuan Wei, Claudia Geißler, Kathrin Abschlag, Judit Corbalán Campos, Michael Hristov, Julia Möllmann, Michael Lehrke, Ela Karshovska, Andreas Schober

Diabetes Dec 2017, 66 (12) 3072-3084; DOI: 10.2337/db17-0313

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