Insulin Strategies for Primary Care Providers

  1. Karen L. Herbst, MD, PhD and
  2. Irl B. Hirsch, MD

    Abstract

    IN BRIEF

    Primary care providers take care of the majority of patients with diabetes in the United States. The introduction of new insulin analogs over the past few years should help primary practitioners and their patients with diabetes achieve physiological insulin replacement and near-normal glucose levels. This article reviews currently available insulins and replacement of insulin in a physiological manner for patients with type 1 or type 2 diabetes and provides examples of patients for whom insulin dosages changed over time.

    Footnotes

    • Karen L. Herbst, MD, PhD, is a senior endocrinology fellow in the Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, and Irl B. Hirsch, MD, is a professor of medicine and medical director of the Diabetes Care Center at the University of Washington School of Medicine in Seattle. Dr. Hirsch is editor-in-chief of Clinical Diabetes.

    • Note of disclosure: Dr. Hirsch serves as a consultant for Aventis Pharmaceuticals, Novo Nordisk, and Eli Lilly and Co. and receives grant support from Novo Nordisk. All three companies manufacture insulin products for the treatment of diabetes.

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