Treating Depression to Prevent Diabetes and Its Complications: Understanding Depression as a Medical Risk Factor
- Monique M. Williams, MD,
- Ray E. Clouse, MD and
- Patrick J. Lustman, PhD
Abstract
IN BRIEF
Current diabetes practice guidelines emphasize the need to augment conventional diabetes therapy with other evidence-based treatments that support improved diabetes outcomes. Clinical depression, much like obesity, is a significant independent risk factor for developing type 2 diabetes and for progression and mortality from type 1 or type 2 diabetes. Effective treatments for depression are available, may enhance glycemic control and insulin sensitivity, and thereby may preserve the physical health and independence of people living with diabetes.
Footnotes
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Monique M. Williams, MD, is an instructor, and Ray E. Clouse, MD, is a professor in the Departments of Psychiatry and Medicine at Washington University School of Medicine in St. Louis, Mo. Patrick J. Lustman, PhD, is a professor in the Department of Psychiatry at Washington University School of Medicine and a counseling psychologist at the Department of Veterans Affairs Medical Center in St. Louis, Mo.
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Note of disclosure: Dr. Clouse and Dr. Lustman have received research funding from GlaxoSmithKline to study the use of its bupropion hydrochloride extended-release tablet product for the treatment of depression in patients with diabetes.
- American Diabetes Association













