Intraoperative Intensive Insulin Therapy Did Not Improve Outcomes Among Patients Undergoing Cardiac Surgery
- Michael Pignone, MD, MPH
STUDY
Gandhi GY, Nuttall GA, Abel MD, Mullany CJ, Schaff HV, O'Brien PC, Johnson MG, Williams AR, Cutshall SM, Mundy LM, Rizza RA, McMahon MM: Intensive intraoperative insulin therapy versus conventional glucose management during cardiac surgery: a randomized trial.
SUMMARY
Design. Randomized, controlled trial at a single academic teaching hospital.
Subjects. Four hundred patients undergoing on-pump cardiac surgery. Mean age was 63 years, 69% were men, 96% were white, and 20% had a history of diabetes.
Methods. Patients were assigned randomly to receive either conventional intraoperative glucose control (treatment for blood glucose …
