TABLE 2.

Criteria for Testing for Diabetes or Prediabetes in Asymptomatic Adults

1. Testing should be considered in all adults who are overweight (BMI ≥25 kg/m2 or ≥23 kg/m2 in Asian Americans) and have additional risk factors:
  • Physical inactivity

  • First-degree relative with diabetes

  • High-risk race/ethnicity (e.g., African American, Latino, Native American, Asian American, Pacific Islander)

  • Women who delivered a baby weighing >9 lb or were diagnosed with GDM

  • Hypertension (≥140/90 mmHg or on therapy for hypertension)

  • HDL cholesterol level <35 mg/dL (0.90 mmol/L) and/or a triglyceride level >250 mg/dL (2.82 mmol/L)

  • Women with polycystic ovary syndrome

  • A1C ≥5.7% (39 mmol/mol), IGT, or IFG on previous testing

  • Other clinical conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans)

  • History of CVD

2. For all patients, testing should begin at age 45 years.
3. If results are normal, testing should be repeated at a minimum of 3-year intervals, with consideration of more frequent testing depending on initial results (e.g., those with prediabetes should be tested yearly) and risk status.
  • IFG, impaired fasting glucose; IGT, impaired glucose tolerance.