TABLE 7.

Recommendations for Statin and Combination Treatment in People With Diabetes

AgeRisk factorsRecommended statin intensity*
<40 yearsNoneNone
ASCVD risk factor(s)**Moderate or high
ASCVDHigh
40–75 yearsNoneModerate
ASCVD risk factorsHigh
ASCVDHigh
ACS and LDL cholesterol >50 mg/dL (1.3 mmol/L) in patients who cannot tolerate high-dose statinsModerate plus ezetimibe
>75 yearsNoneModerate
ASCVD risk factorsModerate or high
ASCVDHigh
ACS and LDL cholesterol >50 mg/dL (1.3 mmol/L) in patients who cannot tolerate high-dose statinsModerate plus ezetimibe
  • * In addition to lifestyle therapy.

  • ** ASCVD risk factors include LDL cholesterol ≥100 mg/dL (2.6 mmol/L), high blood pressure, smoking, overweight and obesity, and family history of premature ASCVD. ACS, acute coronary syndrome.