Clinical Therapeutics/New Technology-Insulins

Clinical Therapeutics/New Technology-Insulins

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Divergent Hypoglycemic Effects of Hepatic-Directed Prandial Insulin: A Six-Month Phase 2b Study in Type 1 Diabetes
David Klonoff, Bruce Bode, Nathan Cohen, Marc Penn, W. Blair Geho, Douglas B. Muchmore

Diabetes Care Sep 2019, dc190152; DOI: 10.2337/dc19-0152
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Baseline Characteristics of Randomized Participants in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE)
Deborah J. Wexler, Heidi Krause-Steinrauf, Jill P. Crandall, Hermes J. Florez, Sophia H. Hox, Alexander Kuhn, Ajay Sood, Chantal Underkofler, Vanita R. Aroda, the GRADE Research Group

Diabetes Care Aug 2019, dc190901; DOI: 10.2337/dc19-0901
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A Randomized Controlled Trial Comparing Efficacy and Safety of Insulin Glargine 300 Units/mL Versus 100 Units/mL in Older People With Type 2 Diabetes: Results From the SENIOR Study
Robert Ritzel, Stewart B. Harris, Helen Baron, Hermes Florez, Ronan Roussel, Melanie Espinasse, Isabel Muehlen-Bartmer, Nianxian Zhang, Monica Bertolini, Claire Brulle-Wohlhueter, Medha Munshi, Geremia B. Bolli

Diabetes Care Aug 2018, 41 (8) 1672-1680; DOI: 10.2337/dc18-0168
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Efficacy and Safety of Fast-Acting Insulin Aspart Compared With Insulin Aspart, Both in Combination With Insulin Degludec, in Children and Adolescents With Type 1 Diabetes: The onset 7 Trial
Bruce W. Bode, Violeta Iotova, Margarita Kovarenko, Lori M. Laffel, Paturi V. Rao, Srikanth Deenadayalan, Magnus Ekelund, Steffen Falgreen Larsen, Thomas Danne

Diabetes Care Jul 2019, 42 (7) 1255-1262; DOI: 10.2337/dc19-0009
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Pharmacokinetics, Pharmacodynamics, and Modulation of Hepatic Glucose Production With Insulin Glargine U300 and Glargine U100 at Steady State With Individualized Clinical Doses in Type 1 Diabetes
Francesca Porcellati, Paola Lucidi, Paola Candeloro, Patrizia Cioli, Anna Marinelli Andreoli, Gianluca Curti, Geremia B. Bolli, Carmine G. Fanelli

Diabetes Care Jan 2019, 42 (1) 85-92; DOI: 10.2337/dc18-0706
Open Access
More Similarities Than Differences Testing Insulin Glargine 300 Units/mL Versus Insulin Degludec 100 Units/mL in Insulin-Naive Type 2 Diabetes: The Randomized Head-to-Head BRIGHT Trial
Julio Rosenstock, Alice Cheng, Robert Ritzel, Zsolt Bosnyak, Christine Devisme, Anna M.G. Cali, Jochen Sieber, Peter Stella, Xiangling Wang, Juan P. Frías, Ronan Roussel, Geremia B. Bolli

Diabetes Care Oct 2018, 41 (10) 2147-2154; DOI: 10.2337/dc18-0559
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Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts
Mary Courtney Moore, David E. Kelley, Raul C. Camacho, Peter Zafian, Tian Ye, Songnian Lin, Niels C. Kaarsholm, Ravi Nargund, Terri M. Kelly, Margaret Van Heek, Stephen F. Previs, Christopher Moyes, Marta S. Smith, Ben Farmer, Phil Williams, Alan D. Cherrington

Diabetes Jun 2018, 67 (6) 1173-1181; DOI: 10.2337/db18-0099
Open Access
Efficacy and Safety of IDegLira Versus Basal-Bolus Insulin Therapy in Patients With Type 2 Diabetes Uncontrolled on Metformin and Basal Insulin: The DUAL VII Randomized Clinical Trial
Liana K. Billings, Ankur Doshi, Didier Gouet, Alejandra Oviedo, Helena W. Rodbard, Nikolaos Tentolouris, Randi Grøn, Natalie Halladin, Esteban Jodar

Diabetes Care May 2018, 41 (5) 1009-1016; DOI: 10.2337/dc17-1114
Open Access
Response to Comment on Russell-Jones et al. Diabetes Care 2017;40:943–950. Comment on Bowering et al. Diabetes Care 2017;40:951–957
Bruce W. Bode, Keith Bowering, David Russell-Jones

Diabetes Care Mar 2018, 41 (3) e29-e30; DOI: 10.2337/dci17-0051
Open Access
Insulin-Induced Distant Site Lipoatrophy
Aki Kondo, Akinobu Nakamura, Jun Takeuchi, Hideaki Miyoshi, Tatsuya Atsumi

Diabetes Care Jun 2017, 40 (6) e67-e68; DOI: 10.2337/dc16-2385

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