Genetics-Type 2 Diabetes

Genetics-Type 2 Diabetes

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Cutaneous Epithelial to Mesenchymal Transition Activator ZEB1 Regulates Wound Angiogenesis and Closure in a Glycemic Status Dependent Manner
Kanhaiya Singh, Mithun Sinha, Durba Pal, Saba Tabasum, Surya C Gnyawali, Dolly Khona, Subendu Sarkar, Sujit K Mohanty, Fidel Soto-Gonzalez, Savita Khanna, Sashwati Roy, Chandan K Sen

Diabetes Aug 2019, db190202; DOI: 10.2337/db19-0202
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Mexican Carriers of the HNF1A p.E508K Variant Do Not Experience an Enhanced Response to Sulfonylureas
Alexandro J. Martagón, Omar Yaxmehen Bello-Chavolla, Olimpia Arellano-Campos, Paloma Almeda-Valdés, Geoffrey A. Walford, Ivette Cruz-Bautista, Donají V. Gómez-Velasco, Roopa Mehta, Liliana Muñoz-Hernández, Magdalena Sevilla-González, Tannia L. Viveros-Ruiz, María Luisa Ordoñez-Sánchez, Rosario Rodríguez-Guillen, Jose C. Florez, María Teresa Tusié-Luna, Carlos A. Aguilar-Salinas

Diabetes Care Aug 2018, 41 (8) 1726-1731; DOI: 10.2337/dc18-0384
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A Genome-Wide Association Study Identifies Blood Disorder–Related Variants Influencing Hemoglobin A_1c With Implications for Glycemic Status in U.S. Hispanics/Latinos
Jee-Young Moon, Tin L. Louie, Deepti Jain, Tamar Sofer, Claudia Schurmann, Jennifer E. Below, Chao-Qiang Lai, M. Larissa Aviles-Santa, Gregory A. Talavera, Caren E. Smith, Lauren E. Petty, Erwin P. Bottinger, Yii-Der Ida Chen, Kent D. Taylor, Martha L. Daviglus, Jianwen Cai, Tao Wang, Katherine L. Tucker, José M. Ordovás, Craig L. Hanis, Ruth J.F. Loos, Neil Schneiderman, Jerome I. Rotter, Robert C. Kaplan, Qibin Qi

Diabetes Care Sep 2019, 42 (9) 1784-1791; DOI: 10.2337/dc19-0168
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Type 2 Diabetes–Associated Genetic Variants Regulate Chromatin Accessibility in Human Islets
Shubham Khetan, Romy Kursawe, Ahrim Youn, Nathan Lawlor, Alexandria Jillette, Eladio J. Marquez, Duygu Ucar, Michael L. Stitzel

Diabetes Nov 2018, 67 (11) 2466-2477; DOI: 10.2337/db18-0393
Open Access
Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans
Neeraj K. Sharma, Chia-Chi Chuang Key, Mete Civelek, Martin Wabitsch, Mary E. Comeau, Carl D. Langefeld, John S. Parks, Swapan K. Das

Diabetes Jul 2019, 68 (7) 1508-1522; DOI: 10.2337/db18-1229
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Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men
Jagadish Vangipurapu, Alena Stancáková, Ulf Smith, Johanna Kuusisto, Markku Laakso

Diabetes Jun 2019, 68 (6) 1353-1358; DOI: 10.2337/db18-1076
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Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study
Adem Y. Dawed, Kaixin Zhou, Nienke van Leeuwen, Anubha Mahajan, Neil Robertson, Robert Koivula, Petra J.M. Elders, Simone P. Rauh, Angus G. Jones, Reinhard W. Holl, Julia C. Stingl, Paul W. Franks, Mark I. McCarthy, Leen M. ‘t Hart, Ewan R. Pearson

Diabetes Care Jun 2019, 42 (6) 1027-1033; DOI: 10.2337/dc18-2182
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Loss-of-Function Mutation in Thiamine Transporter 1 in a Family With Autosomal Dominant Diabetes
Prapaporn Jungtrakoon, Jun Shirakawa, Patinut Buranasupkajorn, Manoj K. Gupta, Dario F. De Jesus, Marcus G. Pezzolesi, Aussara Panya, Timothy Hastings, Chutima Chanprasert, Christine Mendonca, Rohit N. Kulkarni, Alessandro Doria

Diabetes May 2019, 68 (5) 1084-1093; DOI: 10.2337/db17-0821
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DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes
Connor A. Emdin, Amit V. Khera, Krishna Aragam, Mary Haas, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Alexander Bick, Seyedeh M. Zekavat, Akihiro Nomura, Diego Ardissino, James G. Wilson, Heribert Schunkert, Ruth McPherson, Hugh Watkins, Roberto Elosua, Matthew J. Bown, Nilesh J. Samani, Usman Baber, Jeanette Erdmann, Namrata Gupta, John Danesh, Danish Saleheen, Stacey Gabriel, Sekar Kathiresan

Diabetes Jan 2019, 68 (1) 226-234; DOI: 10.2337/db18-0857
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Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes
Chloe Y.Y. Cheung, Chi-Ho Lee, Clara S. Tang, Aimin Xu, Ka-Wing Au, Carol H.Y. Fong, Kelvin K.K. Ng, Kelvin H.M. Kwok, Wing-Sun Chow, Yu-Cho Woo, Michele M.A. Yuen, JoJo Hai, Kathryn C.B. Tan, Tai-Hing Lam, Hung-Fat Tse, Pak-Chung Sham, Karen S.L. Lam

Diabetes Jan 2019, 68 (1) 198-206; DOI: 10.2337/db18-0500

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