Genetics-Type 2 Diabetes

Genetics-Type 2 Diabetes

Open Access
A Global Overview of Precision Medicine in Type 2 Diabetes
Hugo Fitipaldi, Mark I. McCarthy, Jose C. Florez, Paul W. Franks

Diabetes Oct 2018, 67 (10) 1911-1922; DOI: 10.2337/dbi17-0045
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Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population
Soo Heon Kwak, Jeesoo Chae, Seungbok Lee, Sungkyoung Choi, Bo Kyung Koo, Ji Won Yoon, Jin-Ho Park, Belong Cho, Min Kyong Moon, Soo Lim, Young Min Cho, Sanghoon Moon, Young Jin Kim, Sohee Han, Mi Yeong Hwang, Yoon Shin Cho, Myung-Shik Lee, Hak C. Jang, Hyun Min Kang, Taesung Park, Nam H. Cho, Kyunga Kim, Jong-Il Kim, Kyong Soo Park

Diabetes Sep 2018, 67 (9) 1892-1902; DOI: 10.2337/db18-0361
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The Common HNF1A Variant I27L Is a Modifier of Age at Diabetes Diagnosis in Individuals With HNF1A-MODY
Jonathan M. Locke, Cécile Saint-Martin, Thomas W. Laver, Kashyap A. Patel, Andrew R. Wood, Seth A. Sharp, Sian Ellard, Christine Bellanné-Chantelot, Andrew T. Hattersley, Lorna W. Harries, Michael N. Weedon

Diabetes Sep 2018, 67 (9) 1903-1907; DOI: 10.2337/db18-0133
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Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes
Daniel M. Rotroff, Sook Wah Yee, Kaixin Zhou, Skylar W. Marvel, Hetal S. Shah, John R. Jack, Tammy M. Havener, Monique M. Hedderson, Michiaki Kubo, Mark A. Herman, He Gao, Josyf C. Mychaleckyi, Howard L. McLeod, Alessandro Doria, Kathleen M. Giacomini, Ewan R. Pearson, Michael J. Wagner, John B. Buse, Alison A. Motsinger-Reif, MetGen Investigators, ACCORD/ACCORDion Investigators

Diabetes Jul 2018, 67 (7) 1428-1440; DOI: 10.2337/db17-1164
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mtDNA Haplogroup N9a Increases the Risk of Type 2 Diabetes by Altering Mitochondrial Function and Intracellular Mitochondrial Signals
Hezhi Fang, Nianqi Hu, Qiongya Zhao, Bingqian Wang, Huaibin Zhou, Qingzi Fu, Lijun Shen, Xiong Chen, Feixia Shen, Jianxin Lyu

Diabetes Jul 2018, 67 (7) 1441-1453; DOI: 10.2337/db17-0974
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Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis
Janine Kröger, Karina Meidtner, Norbert Stefan, Marcela Guevara, Nicola D. Kerrison, Eva Ardanaz, Dagfinn Aune, Heiner Boeing, Miren Dorronsoro, Courtney Dow, Guy Fagherazzi, Paul W. Franks, Heinz Freisling, Marc J. Gunter, José María Huerta, Rudolf Kaaks, Timothy J. Key, Kay Tee Khaw, Vittorio Krogh, Tilman Kühn, Francesca Romana Mancini, Amalia Mattiello, Peter M. Nilsson, Anja Olsen, Kim Overvad, Domenico Palli, J. Ramón Quirós, Olov Rolandsson, Carlotta Sacerdote, Núria Sala, Elena Salamanca-Fernández, Ivonne Sluijs, Annemieke M.W. Spijkerman, Anne Tjonneland, Konstantinos K. Tsilidis, Rosario Tumino, Yvonne T. van der Schouw, Nita G. Forouhi, Stephen J. Sharp, Claudia Langenberg, Elio Riboli, Matthias B. Schulze, Nicholas J. Wareham

Diabetes Jun 2018, 67 (6) 1200-1205; DOI: 10.2337/db17-1268
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CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets
Yahui Kong, Rohit B. Sharma, Socheata Ly, Rachel E. Stamateris, William M. Jesdale, Laura C. Alonso

Diabetes May 2018, 67 (5) 872-884; DOI: 10.2337/db17-1055
Open Access
Zygodactyly (Syndactyly Type A1) Associated With Midfoot Charcot Neuropathy and Diabetes
Dominic O. McConville, G. Pooler Archbold, Anthony Lewis, Patrick J. Morrison

Diabetes Care May 2018, 41 (5) e74-e75; DOI: 10.2337/dc18-0011
Open Access
Childhood BMI and Adult Type 2 Diabetes, Coronary Artery Diseases, Chronic Kidney Disease, and Cardiometabolic Traits: A Mendelian Randomization Analysis
Tingting Geng, Caren E. Smith, Changwei Li, Tao Huang

Diabetes Care May 2018, 41 (5) 1089-1096; DOI: 10.2337/dc17-2141
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The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function
Xi Chen, Iriscilla Ayala, Chris Shannon, Marcel Fourcaudot, Nikhil K. Acharya, Christopher P. Jenkinson, Sami Heikkinen, Luke Norton

Diabetes Apr 2018, 67 (4) 554-568; DOI: 10.2337/db17-0318

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