Immunology

Immunology

Open Access
The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity
Emil R. Unanue, Xiaoxiao Wan

Diabetes Aug 2019, 68 (8) 1544-1551; DOI: 10.2337/dbi18-0048
Open Access
Successful Treatment of Immune Checkpoint Inhibitor–Induced Diabetes Mellitus With Infliximab
Beckey Trinh, Marc Y. Donath, Heinz Läubli

Diabetes Care Jul 2019, dc190908; DOI: 10.2337/dc19-0908
Open Access
Response to Comment on Mulukutla et al. Autoantibodies to the IA-2 Extracellular Domain Refine the Definition of “A+” Subtypes of Ketosis-Prone Diabetes. Diabetes Care 2018;41:2637–2640
Surya N. Mulukutla, Maria Acevedo-Calado, Christiane S. Hampe, Massimo Pietropaolo, Ashok Balasubramanyam

Diabetes Care May 2019, 42 (5) e82-e83; DOI: 10.2337/dci19-0007
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Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice
Claire E. Macdougall, Elizabeth G. Wood, Antonia Solomou, Valeria Scagliotti, Makoto Mark Taketo, Carles Gaston-Massuet, Federica M. Marelli-Berg, Marika Charalambous, M. Paula Longhi

Diabetes Jul 2019, 68 (7) 1473-1484; DOI: 10.2337/db18-1243
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Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances
Simi Ahmed, Karen Cerosaletti, Eddie James, S. Alice Long, Stuart Mannering, Cate Speake, Maki Nakayama, Timothy Tree, Bart O. Roep, Kevan C. Herold, Todd M. Brusko

Diabetes Jul 2019, 68 (7) 1366-1379; DOI: 10.2337/db19-0119
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Diabetes-Associated Myelopoiesis Drives Stem Cell Mobilopathy Through an OSM-p66Shc Signaling Pathway
Mattia Albiero, Stefano Ciciliot, Serena Tedesco, Lisa Menegazzo, Marianna D’Anna, Valentina Scattolini, Roberta Cappellari, Gaia Zuccolotto, Antonio Rosato, Andrea Cignarella, Marco Giorgio, Angelo Avogaro, Gian Paolo Fadini

Diabetes Jun 2019, 68 (6) 1303-1314; DOI: 10.2337/db19-0080
Open Access
Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA_1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data
Michael J. Haller, S. Alice Long, J. Lori Blanchfield, Desmond A. Schatz, Jay S. Skyler, Jeffrey P. Krischer, Brian N. Bundy, Susan M. Geyer, Megan V. Warnock, Jessica L. Miller, Mark A. Atkinson, Dorothy J. Becker, David A. Baidal, Linda A. DiMeglio, Stephen E. Gitelman, Robin Goland, Peter A. Gottlieb, Kevan C. Herold, Jennifer B. Marks, Antoinette Moran, Henry Rodriguez, William E. Russell, Darrell M. Wilson, Carla J. Greenbaum

Diabetes Jun 2019, 68 (6) 1267-1276; DOI: 10.2337/db19-0057
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T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities
Florian Wiede, Thomas C. Brodnicki, Pei Kee Goh, Yew A. Leong, Gareth W. Jones, Di Yu, Alan G. Baxter, Simon A. Jones, Thomas W.H. Kay, Tony Tiganis

Diabetes Jun 2019, 68 (6) 1251-1266; DOI: 10.2337/db18-1362
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Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression
Tania Habib, S. Alice Long, Peter L. Samuels, Archana Brahmandam, Megan Tatum, Andrew Funk, Anne M. Hocking, Karen Cerosaletti, Michael T. Mason, Elizabeth Whalen, David J. Rawlings, Carla Greenbaum, Jane H. Buckner, the Type 1 Diabetes TrialNet Study Group

Diabetes Jun 2019, 68 (6) 1240-1250; DOI: 10.2337/db18-1081
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HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Mark A. Russell, Sambra D. Redick, David M. Blodgett, Sarah J. Richardson, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Rita Bottino, Marcela Brissova, Jason M. Spaeth, Jenny Aurielle B. Babon, Rachana Haliyur, Alvin C. Powers, Chaoxing Yang, Sally C. Kent, Alan G. Derr, Alper Kucukural, Manuel G. Garber, Noel G. Morgan, David M. Harlan

Diabetes May 2019, 68 (5) 988-1001; DOI: 10.2337/db18-0686

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