Immunology

Immunology

Open Access
The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity
Emil R. Unanue, Xiaoxiao Wan

Diabetes Aug 2019, 68 (8) 1544-1551; DOI: 10.2337/dbi18-0048
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Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody–Positive Individuals
Michelle So, Colin O’Rourke, Henry T. Bahnson, Carla J. Greenbaum, Cate Speake

Diabetes Care Apr 2020, 43 (4) 913-917; DOI: 10.2337/dc19-1731
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Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr⁺ Treg Cells
Luigi Cari, Pia Montanucci, Giuseppe Basta, Maria G. Petrillo, Erika Ricci, Teresa Pescara, Alessia Greco, Sabrina Cipriani, Jun Shimizu, Graziella Migliorati, Giuseppe Nocentini, Riccardo Calafiore, Carlo Riccardi

Diabetes May 2020, 69 (5) 965-980; DOI: 10.2337/db19-0087
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NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation
Francis M. Hughes, Nathan A. Hirshman, Brian M. Inouye, Huixia Jin, Eloise W. Stanton, Chloe E. Yun, Leah G. Davis, Jonathan C. Routh, J. Todd Purves

Diabetes Feb 2019, 68 (2) 430-440; DOI: 10.2337/db18-0845
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HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Mark A. Russell, Sambra D. Redick, David M. Blodgett, Sarah J. Richardson, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Rita Bottino, Marcela Brissova, Jason M. Spaeth, Jenny Aurielle B. Babon, Rachana Haliyur, Alvin C. Powers, Chaoxing Yang, Sally C. Kent, Alan G. Derr, Alper Kucukural, Manuel G. Garber, Noel G. Morgan, David M. Harlan

Diabetes May 2019, 68 (5) 988-1001; DOI: 10.2337/db18-0686
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Altered Gut Microbiota Activate and Expand Insulin B15-23–Reactive CD8+ T Cells
James A. Pearson, Dimitri Kakabadse, Joanne Davies, Jian Peng, Jeremy Warden-Smith, Simone Cuff, Mark Lewis, Larissa Camargo da Rosa, Li Wen, F. Susan Wong

Diabetes May 2019, 68 (5) 1002-1013; DOI: 10.2337/db18-0487
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FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing
Mohammed A. Alharbi, Citong Zhang, Chanyi Lu, Tatyana N. Milovanova, Leah Yi, Je Dong Ryu, Hongli Jiao, Guangyu Dong, J. Patrick O’Connor, Dana T. Graves

Diabetes Dec 2018, 67 (12) 2682-2694; DOI: 10.2337/db18-0340
Open Access
Hybrid Insulin Peptides Are Autoantigens in Type 1 Diabetes
Rocky L. Baker, Marynette Rihanek, Anita C. Hohenstein, Maki Nakayama, Aaron Michels, Peter A. Gottlieb, Kathryn Haskins, Thomas Delong

Diabetes Sep 2019, 68 (9) 1830-1840; DOI: 10.2337/db19-0128
Open Access
Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes
Maria J. Acevedo-Calado, Susan L. Pietropaolo, Michael P. Morran, Santiago Schnell, Andrew D. Vonberg, Charles F. Verge, Roberto Gianani, Dorothy J. Becker, Shuai Huang, Carla J. Greenbaum, Liping Yu, Howard W. Davidson, Aaron W. Michels, Stephen S. Rich, Massimo Pietropaolo

Diabetes Sep 2019, 68 (9) 1819-1829; DOI: 10.2337/db18-1351
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Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children
David Endesfelder, Wolfgang zu Castell, Ezio Bonifacio, Marian Rewers, William A. Hagopian, Jin‐Xiong She, Åke Lernmark, Jorma Toppari, Kendra Vehik, Alistair J.K. Williams, Liping Yu, Beena Akolkar, Jeffrey P. Krischer, Anette-G. Ziegler, Peter Achenbach

Diabetes Jan 2019, 68 (1) 119-130; DOI: 10.2337/db18-0594

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