Immunology

Immunology

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Autoantibody Reversion: Changing Risk Categories in Multiple-Autoantibody–Positive Individuals
Michelle So, Colin O’Rourke, Henry T. Bahnson, Carla J. Greenbaum, Cate Speake

Diabetes Care Apr 2020, 43 (4) 913-917; DOI: 10.2337/dc19-1731
Open Access
Modulation of Leukocytes of the Innate Arm of the Immune System as a Potential Approach to Prevent the Onset and Progression of Type 1 Diabetes
Alessandra Petrelli, Mark A. Atkinson, Massimo Pietropaolo, Nick Giannoukakis

Diabetes Feb 2021, 70 (2) 313-322; DOI: 10.2337/dbi20-0026
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Baseline Assessment of Circulating MicroRNAs Near Diagnosis of Type 1 Diabetes Predicts Future Stimulated Insulin Secretion
Isaac Snowhite, Ricardo Pastori, Jay Sosenko, Shari Messinger Cayetano, Alberto Pugliese

Diabetes Feb 2021, 70 (2) 638-651; DOI: 10.2337/db20-0817
Open Access
Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice
Fernanda M.C. Sodré, Samal Bissenova, Ylke Bruggeman, Ronak Tilvawala, Dana P. Cook, Claire Berthault, Santanu Mondal, Aïsha Callebaut, Sylvaine You, Raphael Scharfmann, Roberto Mallone, Paul R. Thompson, Chantal Mathieu, Mijke Buitinga, Lut Overbergh

Diabetes Feb 2021, 70 (2) 516-528; DOI: 10.2337/db20-0421
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TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model
Sha Sha, James A. Pearson, Jian Peng, Youjia Hu, Juan Huang, Yanpeng Xing, Luyao Zhang, Ying Zhu, Hongyu Zhao, F. Susan Wong, Li Chen, Li Wen

Diabetes Feb 2021, 70 (2) 504-515; DOI: 10.2337/db20-0373
Open Access
Multinucleated Giant Cells in Adipose Tissue Are Specialized in Adipocyte Degradation
Julia Braune, Andreas Lindhorst, Janine Fröba, Constance Hobusch, Peter Kovacs, Matthias Blüher, Jens Eilers, Ingo Bechmann, Martin Gericke

Diabetes Feb 2021, 70 (2) 538-548; DOI: 10.2337/db20-0293
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Differentiating MHC-Dependent and -Independent Mechanisms of Lymph Node Stromal Cell Regulation of Proinsulin-Specific CD8⁺ T Cells in Type 1 Diabetes
Terri C. Thayer, Joanne Davies, James A. Pearson, Stephanie J. Hanna, Li Wen, F. Susan Wong

Diabetes Feb 2021, 70 (2) 529-537; DOI: 10.2337/db19-1050
Open Access
InsB9-23 Gene Transfer to Hepatocyte-Based Combined Therapy Abrogates Recurrence of Type 1 Diabetes After Islet Transplantation
Fabio Russo, Antonio Citro, Giorgia Squeri, Francesca Sanvito, Paolo Monti, Silvia Gregori, Maria Grazia Roncarolo, Andrea Annoni

Diabetes Jan 2021, 70 (1) 171-181; DOI: 10.2337/db19-1249
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HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
Mark A. Russell, Sambra D. Redick, David M. Blodgett, Sarah J. Richardson, Pia Leete, Lars Krogvold, Knut Dahl-Jørgensen, Rita Bottino, Marcela Brissova, Jason M. Spaeth, Jenny Aurielle B. Babon, Rachana Haliyur, Alvin C. Powers, Chaoxing Yang, Sally C. Kent, Alan G. Derr, Alper Kucukural, Manuel G. Garber, Noel G. Morgan, David M. Harlan

Diabetes May 2019, 68 (5) 988-1001; DOI: 10.2337/db18-0686
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Altered Gut Microbiota Activate and Expand Insulin B15-23–Reactive CD8+ T Cells
James A. Pearson, Dimitri Kakabadse, Joanne Davies, Jian Peng, Jeremy Warden-Smith, Simone Cuff, Mark Lewis, Larissa Camargo da Rosa, Li Wen, F. Susan Wong

Diabetes May 2019, 68 (5) 1002-1013; DOI: 10.2337/db18-0487

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