Integrated Physiology-Other Hormones

Integrated Physiology-Other Hormones

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No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes
Natasha C. Bergmann, Lærke S. Gasbjerg, Sebastian M. Heimbürger, Liva S.L. Krogh, Flemming Dela, Bolette Hartmann, Jens J. Holst, Lene Jessen, Mikkel B. Christensen, Tina Vilsbøll, Asger Lund, Filip K. Knop

Diabetes Care Jan 2020, dc190578; DOI: 10.2337/dc19-0578
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Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension
Yingjie Ji, Andrianos M. Yiorkas, Francesca Frau, Dennis Mook-Kanamori, Harald Staiger, E. Louise Thomas, Naeimeh Atabaki-Pasdar, Archie Campbell, Jessica Tyrrell, Samuel E. Jones, Robin N. Beaumont, Andrew R. Wood, Marcus A. Tuke, Katherine S. Ruth, Anubha Mahajan, Anna Murray, Rachel M. Freathy, Michael N. Weedon, Andrew T. Hattersley, Caroline Hayward, Jürgen Machann, Hans-Ulrich Häring, Paul Franks, Renée de Mutsert, Ewan Pearson, Norbert Stefan, Timothy M. Frayling, Karla V. Allebrandt, Jimmy D. Bell, Alexandra I. Blakemore, Hanieh Yaghootkar

Diabetes Jan 2019, 68 (1) 207-219; DOI: 10.2337/db18-0708
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GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner
Yanqing Zhang, Keshab R. Parajuli, Genevieve E. Fava, Rajesh Gupta, Weiwei Xu, Lauren U. Nguyen, Anadil F. Zakaria, Vivian A. Fonseca, Hongjun Wang, Franck Mauvais-Jarvis, Kyle W. Sloop, Hongju Wu

Diabetes Jan 2019, 68 (1) 34-44; DOI: 10.2337/db18-0317
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Excitatory GABAergic Action and Increased Vasopressin Synthesis in Hypothalamic Magnocellular Neurosecretory Cells Underlie the High Plasma Level of Vasopressin in Diabetic Rats
Young-Beom Kim, Woong Bin Kim, Won Woo Jung, Xiangyan Jin, Yoon Sik Kim, Byoungjae Kim, Hee Chul Han, Gene D. Block, Christopher S. Colwell, Yang In Kim

Diabetes Mar 2018, 67 (3) 486-495; DOI: 10.2337/db17-1042
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Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase
Lotta E. Andersson, Liliya Shcherbina, Mahmoud Al-Majdoub, Neelanjan Vishnu, Claudia Balderas Arroyo, Jonathan Aste Carrara, Claes B. Wollheim, Malin Fex, Hindrik Mulder, Nils Wierup, Peter Spégel

Diabetes Mar 2018, 67 (3) 372-384; DOI: 10.2337/db16-1441
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Impaired Sensitivity to Thyroid Hormones Is Associated With Diabetes and Metabolic Syndrome
Martin Laclaustra, Belen Moreno-Franco, Jose Manuel Lou-Bonafonte, Rocio Mateo-Gallego, Jose Antonio Casasnovas, Pilar Guallar-Castillon, Ana Cenarro, Fernando Civeira

Diabetes Care Feb 2019, 42 (2) 303-310; DOI: 10.2337/dc18-1410
Open Access
Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized, Single-Blinded, Placebo-Controlled Study
Preeshila Behary, George Tharakan, Kleopatra Alexiadou, Nicholas Johnson, Nicolai J. Wewer Albrechtsen, Julia Kenkre, Joyceline Cuenco, David Hope, Oluwaseun Anyiam, Sirazum Choudhury, Haya Alessimii, Ankur Poddar, James Minnion, Chedie Doyle, Gary Frost, Carel Le Roux, Sanjay Purkayastha, Krishna Moorthy, Waljit Dhillo, Jens J. Holst, Ahmed R. Ahmed, A. Toby Prevost, Stephen R. Bloom, Tricia M. Tan

Diabetes Care Aug 2019, 42 (8) 1446-1453; DOI: 10.2337/dc19-0449
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Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of K_ATP Channel Blockers
Bao-Khanh Lai, Heeyoung Chae, Ana Gómez-Ruiz, Panpan Cheng, Paola Gallo, Nancy Antoine, Christophe Beauloye, Jean-Christophe Jonas, Victor Seghers, Susumu Seino, Patrick Gilon

Diabetes Nov 2018, 67 (11) 2239-2253; DOI: 10.2337/db17-0880
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Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production
Zhuo Mao, Hui Lin, Wen Su, Jinghui Li, Minsi Zhou, Zhuoran Li, Beibei Zhou, Qing Yang, Mingyan Zhou, Ke Pan, Jinhan He, Weizhen Zhang

Diabetes Jun 2019, 68 (6) 1197-1209; DOI: 10.2337/db18-1321
Open Access
Melatonin Increases Brown Adipose Tissue Volume and Activity in Patients With Melatonin Deficiency: A Proof-of-Concept Study
Bruno Halpern, Marcio C. Mancini, Clarissa Bueno, Isabella P. Barcelos, Maria Edna de Melo, Marcos S. Lima, Camila G. Carneiro, Marcelo T. Sapienza, Carlos Alberto Buchpiguel, Fernanda Gaspar do Amaral, José Cipolla-Neto

Diabetes May 2019, 68 (5) 947-952; DOI: 10.2337/db18-0956

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