Islet Biology-Apoptosis

Islet Biology-Apoptosis

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A Phenotypic Screen Identifies Calcium Overload as a Key Mechanism of β-Cell Glucolipotoxicity
Jennifer Vogel, Jianning Yin, Liansheng Su, Sharon X. Wang, Richard Zessis, Sena Fowler, Chun-Hao Chiu, Aaron C. Wilson, Amy Chen, Frederic Zecri, Gordon Turner, Thomas M. Smith, Brian DeChristopher, Heming Xing, Deborah M. Rothman, Xinming Cai, Alina Berdichevsky

Diabetes May 2020, 69 (5) 1032-1041; DOI: 10.2337/db19-0813
Open Access
SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
Tina Fløyel, Kira Meyerovich, Michala C. Prause, Simranjeet Kaur, Caroline Frørup, Henrik B. Mortensen, Lotte B. Nielsen, Flemming Pociot, Alessandra K. Cardozo, Joachim Størling

Diabetes Feb 2021, 70 (2) 464-476; DOI: 10.2337/db20-0092
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Lactogens Reduce Endoplasmic Reticulum Stress–Induced Rodent and Human β-Cell Death and Diabetes Incidence in Akita Mice
Rosemary Li, Nagesha Guthalu Kondegowda, Joanna Filipowska, Rollie F. Hampton, Silvia Leblanc, Adolfo Garcia-Ocana, Rupangi C. Vasavada

Diabetes Jul 2020, 69 (7) 1463-1475; DOI: 10.2337/db19-0909
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Islets for Research: Nothing Is Perfect, but We Can Do Better
Rita Nano, Julie A. Kerr-Conte, Domenico Bosco, Marie Karlsson, Vanessa Lavallard, Raffaella Melzi, Valery Gmyr, Alessia Mercalli, Thierry Berney, François Pattou, Olle Korsgren, Lorenzo Piemonti

Diabetes Aug 2019, 68 (8) 1541-1543; DOI: 10.2337/db19-0367
Open Access
Hyperuricemia Predisposes to the Onset of Diabetes via Promoting Pancreatic β-Cell Death in Uricase-Deficient Male Mice
Jie Lu, Yuwei He, Lingling Cui, Xiaoming Xing, Zhen Liu, Xinde Li, Hui Zhang, Hailong Li, Wenyan Sun, Aichang Ji, Yao Wang, Huiyong Yin, Changgui Li

Diabetes Jun 2020, 69 (6) 1149-1163; DOI: 10.2337/db19-0704
Open Access
Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes
Anne Jörns, Dirk Wedekind, Joachim Jähne, Sigurd Lenzen

Diabetes Apr 2020, 69 (4) 624-633; DOI: 10.2337/db19-0865
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De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction
Elisa De Franco, Richard Caswell, Matthew B. Johnson, Matthew N. Wakeling, Amnon Zung, Vũ Chí Dũng, Cấn Thị Bích Ngọc, Rajiv Goonetilleke, Maritza Vivanco Jury, Mohammed El-Khateeb, Sian Ellard, Sarah E. Flanagan, David Ron, Andrew T. Hattersley

Diabetes Mar 2020, 69 (3) 477-483; DOI: 10.2337/db19-1029
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Nutrient-Induced Metabolic Stress, Adaptation, Detoxification, and Toxicity in the Pancreatic β-Cell
Marc Prentki, Marie-Line Peyot, Pellegrino Masiello, S.R. Murthy Madiraju

Diabetes Mar 2020, 69 (3) 279-290; DOI: 10.2337/dbi19-0014
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MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic β-Cell Mass in Mice
Tatiana Danilova, Ilya Belevich, Huini Li, Erik Palm, Eija Jokitalo, Timo Otonkoski, Maria Lindahl

Diabetes Jan 2019, 68 (1) 66-80; DOI: 10.2337/db17-1149
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SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival
Jonàs Juan-Mateu, Maria Inês Alvelos, Jean-Valéry Turatsinze, Olatz Villate, Esther Lizarraga-Mollinedo, Fabio Arturo Grieco, Laura Marroquí, Marco Bugliani, Piero Marchetti, Décio L. Eizirik

Diabetes Mar 2018, 67 (3) 423-436; DOI: 10.2337/db17-0736

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