Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Open Access
Pancreatic β-Cell–Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion
Christian H. Burns, Belinda Yau, Anjelica Rodriguez, Jenna Triplett, Drew Maslar, You Sun An, Reini E.N. van der Welle, Ross G. Kossina, Max R. Fisher, Gregory W. Strout, Peter O. Bayguinov, Tineke Veenendaal, David Chitayat, James A.J. Fitzpatrick, Judith Klumperman, Melkam A. Kebede, Cedric S. Asensio

Diabetes Feb 2021, 70 (2) 436-448; DOI: 10.2337/db20-0454
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Acyl-Ghrelin Influences Pancreatic β-Cell Function by Interference with K_ATP Channels
Julia Kaiser, Peter Krippeit-Drews, Gisela Drews

Diabetes Feb 2021, 70 (2) 423-435; DOI: 10.2337/db20-0231
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Retinol-Binding Protein 4 Activates STRA6, Provoking Pancreatic β-Cell Dysfunction in Type 2 Diabetes
Rong Huang, Xinxiu Bai, Xueyan Li, Xiaohui Wang, Lina Zhao

Diabetes Feb 2021, 70 (2) 449-463; DOI: 10.2337/db19-1241
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HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice
Tijun Wu, Shuang Zhang, Jialiang Xu, Yaqin Zhang, Tong Sun, Yixue Shao, Jiahui Wang, Wei Tang, Fang Chen, Xiao Han

Diabetes May 2020, 69 (5) 940-953; DOI: 10.2337/db19-1060
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“Take Me To Your Leader”: An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets
Leslie S. Satin, Quan Zhang, Patrik Rorsman

Diabetes May 2020, 69 (5) 830-836; DOI: 10.2337/dbi19-0012
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Dynamic Uni- and Multicellular Patterns Encode Biphasic Activity in Pancreatic Islets
Manon Jaffredo, Eléonore Bertin, Antoine Pirog, Emilie Puginier, Julien Gaitan, Sandra Oucherif, Fanny Lebreton, Domenico Bosco, Bogdan Catargi, Daniel Cattaert, Sylvie Renaud, Jochen Lang, Matthieu Raoux

Diabetes Apr 2021, 70 (4) 878-888; DOI: 10.2337/db20-0214
Open Access
Lifting the Veil on the “Phosphate Flush,” a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology
Franz Matschinsky, David Wilson

Diabetes Jan 2021, 70 (1) 27-28; DOI: 10.2337/dbi20-0038
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Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity
Xing Ming, Arthur C.K. Chung, Dandan Mao, Huanyi Cao, Baoqi Fan, Willy K.K. Wong, Chin Chung Ho, Heung Man Lee, Kristina Schoonjans, Johan Auwerx, Guy A. Rutter, Juliana C.N. Chan, Xiao Yu Tian, Alice P.S. Kong

Diabetes Jan 2021, 70 (1) 119-131; DOI: 10.2337/db20-0339
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Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function
Seokwon Jo, Amber Lockridge, Ramkumar Mohan, Nicholas Esch, Regina Schlichting, Neha Panigrahy, Ahmad Essawy, Eric Gustafson, Emilyn U. Alejandro

Diabetes Jan 2021, 70 (1) 155-170; DOI: 10.2337/db20-0057
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Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Weiwei Xu, Lina Schiffer, M.M. Fahd Qadir, Yanqing Zhang, James Hawley, Paula Mota De Sa, Brian G. Keevil, Hongju Wu, Wiebke Arlt, Franck Mauvais-Jarvis

Diabetes Nov 2020, 69 (11) 2392-2399; DOI: 10.2337/db20-0228

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