Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Open Access
Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells
Siming Liu, Joseph A. Promes, Mikako Harata, Akansha Mishra, Samuel B. Stephens, Eric B. Taylor, Anthony J. Burand, William I. Sivitz, Brian D. Fink, James A. Ankrum, Yumi Imai

Diabetes Jun 2020, 69 (6) 1178-1192; DOI: 10.2337/db19-0951
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Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signaling
Jonathan R. Weitz, Carol Jacques-Silva, Mirza Muhammed Fahd Qadir, Oliver Umland, Elizabeth Pereira, Farhan Qureshi, Alejandro Tamayo, Juan Dominguez-Bendala, Rayner Rodriguez-Diaz, Joana Almaça, Alejandro Caicedo

Diabetes Jun 2020, 69 (6) 1206-1218; DOI: 10.2337/db19-0687
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HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice
Tijun Wu, Shuang Zhang, Jialiang Xu, Yaqin Zhang, Tong Sun, Yixue Shao, Jiahui Wang, Wei Tang, Fang Chen, Xiao Han

Diabetes May 2020, 69 (5) 940-953; DOI: 10.2337/db19-1060
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“Take Me To Your Leader”: An Electrophysiological Appraisal of the Role of Hub Cells in Pancreatic Islets
Leslie S. Satin, Quan Zhang, Patrik Rorsman

Diabetes May 2020, 69 (5) 830-836; DOI: 10.2337/dbi19-0012
Open Access
The Local Paracrine Actions of the Pancreatic α-Cell
Rayner Rodriguez-Diaz, Alejandro Tamayo, Manami Hara, Alejandro Caicedo

Diabetes Apr 2020, 69 (4) 550-558; DOI: 10.2337/dbi19-0002
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Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally
Holly A. Cyphert, Emily M. Walker, Yan Hang, Sangeeta Dhawan, Rachana Haliyur, Lauren Bonatakis, Dana Avrahami, Marcela Brissova, Klaus H. Kaestner, Anil Bhushan, Alvin C. Powers, Roland Stein

Diabetes Feb 2019, 68 (2) 337-348; DOI: 10.2337/db18-0903
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TGR5 Activation Promotes Stimulus-Secretion Coupling of Pancreatic β-Cells via a PKA-Dependent Pathway
Jonas Maczewsky, Julia Kaiser, Anne Gresch, Felicia Gerst, Martina Düfer, Peter Krippeit-Drews, Gisela Drews

Diabetes Feb 2019, 68 (2) 324-336; DOI: 10.2337/db18-0315
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Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass
Eunjin Oh, Miwon Ahn, Solomon Afelik, Thomas C. Becker, Bart O. Roep, Debbie C. Thurmond

Diabetes Dec 2018, 67 (12) 2626-2639; DOI: 10.2337/db18-0259
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Intraislet Ghrelin Signaling Does Not Regulate Insulin Secretion From Adult Mice
Sarah M. Gray, Jingjing Niu, Amanda Zhang, Berit Svendsen, Jonathan E. Campbell, David A. D’Alessio, Jenny Tong

Diabetes Sep 2019, 68 (9) 1795-1805; DOI: 10.2337/db19-0079
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Differential Effect of Glucose on ER-Mitochondria Ca²⁺ Exchange Participates in Insulin Secretion and Glucotoxicity-Mediated Dysfunction of β-Cells
Florian Dingreville, Baptiste Panthu, Charles Thivolet, Sylvie Ducreux, Yves Gouriou, Sandra Pesenti, Marie-Agnès Chauvin, Karim Chikh, Elisabeth Errazuriz-Cerda, Fabien Van Coppenolle, Jennifer Rieusset, Anne-Marie Madec

Diabetes Sep 2019, 68 (9) 1778-1794; DOI: 10.2337/db18-1112

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