Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Open Access
Pancreatic β-Cell–Specific Deletion of VPS41 Causes Diabetes Due to Defects in Insulin Secretion
Christian H. Burns, Belinda Yau, Anjelica Rodriguez, Jenna Triplett, Drew Maslar, You Sun An, Reini E.N. van der Welle, Ross G. Kossina, Max R. Fisher, Gregory W. Strout, Peter O. Bayguinov, Tineke Veenendaal, David Chitayat, James A.J. Fitzpatrick, Judith Klumperman, Melkam A. Kebede, Cedric S. Asensio

Diabetes Feb 2021, 70 (2) 436-448; DOI: 10.2337/db20-0454
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Acyl-Ghrelin Influences Pancreatic β-Cell Function by Interference with K_ATP Channels
Julia Kaiser, Peter Krippeit-Drews, Gisela Drews

Diabetes Feb 2021, 70 (2) 423-435; DOI: 10.2337/db20-0231
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Retinol-Binding Protein 4 Activates STRA6, Provoking Pancreatic β-Cell Dysfunction in Type 2 Diabetes
Rong Huang, Xinxiu Bai, Xueyan Li, Xiaohui Wang, Lina Zhao

Diabetes Feb 2021, 70 (2) 449-463; DOI: 10.2337/db19-1241
Open Access
Lifting the Veil on the “Phosphate Flush,” a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology
Franz Matschinsky, David Wilson

Diabetes Jan 2021, 70 (1) 27-28; DOI: 10.2337/dbi20-0038
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Pancreatic Sirtuin 3 Deficiency Promotes Hepatic Steatosis by Enhancing 5-Hydroxytryptamine Synthesis in Mice With Diet-Induced Obesity
Xing Ming, Arthur C.K. Chung, Dandan Mao, Huanyi Cao, Baoqi Fan, Willy K.K. Wong, Chin Chung Ho, Heung Man Lee, Kristina Schoonjans, Johan Auwerx, Guy A. Rutter, Juliana C.N. Chan, Xiao Yu Tian, Alice P.S. Kong

Diabetes Jan 2021, 70 (1) 119-131; DOI: 10.2337/db20-0339
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Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function
Seokwon Jo, Amber Lockridge, Ramkumar Mohan, Nicholas Esch, Regina Schlichting, Neha Panigrahy, Ahmad Essawy, Eric Gustafson, Emilyn U. Alejandro

Diabetes Jan 2021, 70 (1) 155-170; DOI: 10.2337/db20-0057
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Intracrine Testosterone Activation in Human Pancreatic β-Cells Stimulates Insulin Secretion
Weiwei Xu, Lina Schiffer, M.M. Fahd Qadir, Yanqing Zhang, James Hawley, Paula Mota De Sa, Brian G. Keevil, Hongju Wu, Wiebke Arlt, Franck Mauvais-Jarvis

Diabetes Nov 2020, 69 (11) 2392-2399; DOI: 10.2337/db20-0228
Open Access
VMAT2 Safeguards β-Cells Against Dopamine Cytotoxicity Under High-Fat Diet–Induced Stress
Daisuke Sakano, Fumiya Uefune, Hiraku Tokuma, Yuki Sonoda, Kumi Matsuura, Naoki Takeda, Naomi Nakagata, Kazuhiko Kume, Nobuaki Shiraki, Shoen Kume

Diabetes Nov 2020, 69 (11) 2377-2391; DOI: 10.2337/db20-0207
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Pancreatic Islets and Gestalt Principles
Michael P. Dybala, John K. Butterfield, Bryce K. Hendren-Santiago, Manami Hara

Diabetes Sep 2020, 69 (9) 1864-1874; DOI: 10.2337/db20-0304
Open Access
Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells
Siming Liu, Joseph A. Promes, Mikako Harata, Akansha Mishra, Samuel B. Stephens, Eric B. Taylor, Anthony J. Burand, William I. Sivitz, Brian D. Fink, James A. Ankrum, Yumi Imai

Diabetes Jun 2020, 69 (6) 1178-1192; DOI: 10.2337/db19-0951

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