Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

Islet Biology-Beta Cell-Stimulus-Secretion Coupling and Metabolism

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Intraislet Ghrelin Signaling Does Not Regulate Insulin Secretion From Adult Mice
Sarah M. Gray, Jingjing Niu, Amanda Zhang, Berit Svendsen, Jonathan E. Campbell, David A. D’Alessio, Jenny Tong

Diabetes Sep 2019, 68 (9) 1795-1805; DOI: 10.2337/db19-0079
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Differential Effect of Glucose on ER-Mitochondria Ca²⁺ Exchange Participates in Insulin Secretion and Glucotoxicity-Mediated Dysfunction of β-Cells
Florian Dingreville, Baptiste Panthu, Charles Thivolet, Sylvie Ducreux, Yves Gouriou, Sandra Pesenti, Marie-Agnès Chauvin, Karim Chikh, Elisabeth Errazuriz-Cerda, Fabien Van Coppenolle, Jennifer Rieusset, Anne-Marie Madec

Diabetes Sep 2019, 68 (9) 1778-1794; DOI: 10.2337/db18-1112
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Impact of Insulin and Metformin Versus Metformin Alone on β-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes
The RISE Consortium

Diabetes Care Aug 2018, 41 (8) 1717-1725; DOI: 10.2337/dc18-0787
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Glucolipotoxicity Alters Insulin Secretion via Epigenetic Changes in Human Islets
Elin Hall, Josefine Jönsson, Jones K. Ofori, Petr Volkov, Alexander Perfilyev, Marloes Dekker Nitert, Lena Eliasson, Charlotte Ling, Karl Bacos

Diabetes Oct 2019, 68 (10) 1965-1974; DOI: 10.2337/db18-0900
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Glucolipotoxicity-Inhibited miR-299-5p Regulates Pancreatic β-Cell Function and Survival
Qiqing Huang, Weiyan You, Yating Li, Yi Sun, Yuncai Zhou, Yan Zhang, Dechen Liu, Shanshan Zhan, Yunxia Zhu, Xiao Han

Diabetes Nov 2018, 67 (11) 2280-2292; DOI: 10.2337/db18-0223
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Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell
Tatsuyoshi Kono, Xin Tong, Solaema Taleb, Robert N. Bone, Hitoshi Iida, Chih-Chun Lee, Paul Sohn, Patrick Gilon, Michael W. Roe, Carmella Evans-Molina

Diabetes Nov 2018, 67 (11) 2293-2304; DOI: 10.2337/db17-1351
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Whole-Organism Chemical Screening Identifies Modulators of Pancreatic β-Cell Function
Hiroki Matsuda, Sri Teja Mullapudi, Yu Hsuan Carol Yang, Hideki Masaki, Daniel Hesselson, Didier Y.R. Stainier

Diabetes Nov 2018, 67 (11) 2268-2279; DOI: 10.2337/db17-1223
Open Access
Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258–264
Emily K. Sims, Henry T. Bahnson, Julius Nyalwidhe, Leena Haataja, Asa K. Davis, Cate Speake, Linda A. DiMeglio, Janice Blum, Margaret A. Morris, Raghavendra G. Mirmira, Jerry Nadler, Teresa L. Mastracci, Santica Marcovina, Wei-Jun Qian, Lian Yi, Adam C. Swensen, Michele Yip-Schneider, C. Max Schmidt, Robert V. Considine, Peter Arvan, Carla J. Greenbaum, Carmella Evans-Molina

Diabetes Care May 2019, 42 (5) e85-e86; DOI: 10.2337/dci19-0012
Open Access
Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258–264
Devin W. Steenkamp, Jose M. Cacicedo, Catherine A. Sullivan

Diabetes Care May 2019, 42 (5) e84; DOI: 10.2337/dc19-0158
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β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity
Teresa Mezza, Francesca Cinti, Chiara Maria Assunta Cefalo, Alfredo Pontecorvi, Rohit N. Kulkarni, Andrea Giaccari

Diabetes Jun 2019, 68 (6) 1121-1129; DOI: 10.2337/db18-0856

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