LDL Cholesterol Lowering in Type 2 Diabetes: What Is the Optimum Approach?

Abstract

IN BRIEF

Managing the high risk for cardiovascular morbidity and mortality in diabetic patients is a challenge for practicing clinicians. Reducing the burden of cardiovascular disease in diabetes should begin with assessment and treatment of elevated LDL cholesterol. Statins are the preferred treatment, and intensive statin therapy may be necessary to meet the current goal of < 100 mg/dl or the optional goal of < 70 mg/dl recommended for high-risk patients and to address other components of diabetic dyslipidemia. Along with aggressive glucose and blood pressure control, intensive treatment of LDL cholesterol in patients with diabetes can substantially affect long-term health outcomes.