TABLE 2.

Distribution of Self-Reported GI Symptoms in the Look AHEAD Cohort Over Time by Treatment Group

GI ConditionPercentage With Condition at:Treatment Group P*Time P*Treatment Group by Time P*
BaselineYear 1Year 2Year 3Year 4
Abdominal pain above navelDSE10.512.512.813.614.00.440.00020.22
ILI11.411.012.213.112.4
Abdominal pain below navelDSE14.717.417.117.918.60.280.00080.08
ILI15.715.216.117.516.4
ConstipationDSE28.231.933.235.535.60.03<0.00010.003
ILI29.037.835.637.436.4
DiarrheaDSE33.135.235.535.835.60.00050.510.27
ILI31.932.031.032.231.5
Feeling very full after eating littleDSE16.619.320.923.221.80.05<0.00010.0005
ILI17.915.918.219.121.4
HeartburnDSE35.136.636.436.236.20.0002<0.0001<0.0001
ILI35.326.929.834.435.4
NauseaDSE16.621.522.322.821.90.16<0.00010.0007
ILI18.818.618.821.221.8
Bloating or distentionDSE38.841.438.937.838.10.490.03<0.0001
ILI41.436.837.838.836.4
RegurgitationDSE18.220.721.320.823.20.0001<0.0001<0.0001
ILI19.714.516.218.720.1
VomitingDSE4.36.66.77.47.90.009<0.00010.26
ILI4.35.14.76.76.5
  • * Models of change in prevalence from baseline are adjusted for repeated measures.