TABLE 1.

Summary of Studies of U-500 Delivered via CSII

StudySubjects (n)Mean Duration (months)Mean Baseline A1C (%)Mean A1C Reduction (%)Mean Baseline TDD (units)Mean TDD Change (units)Mean Weight Change (kg)
Knee et al., 2003 (20)4610.83.5334–120N/A
Schwartz, 2004 (26)5N/A10.242.49410N/A4.5
Lane, 2006 (21)938.81.13172–5.31.9
Bulchandani et al., 2007 (19)669.12.2391–95–2.8
Lane et al., 2010 (23)21128.61.23197125.4