TABLE 1.

Recommendations for Basal Insulin Therapy Initiation

Treatment GuidelinesStarting Dose of InsulinInsulin Dose IncrementsFrequencyMaximum Insulin DoseTarget FPG, mg/dL
ADA/EASD (1,3)10 units/day or 0.1−0.2 units/kg/day5−15% or 1−4 units1−2 times per week0.5 units/kg/day80–130
AACE/ACE (2)0.1−0.2 units/kg/day for A1C <8.0%; 0.2−0.3 units/kg/day for A1C >8.0%2 units for fixed regimenEvery 2−3 days<110*
IDF (18)2 unitsEvery 3 days<115
  • * Target FBG. IDF, International Diabetes Federation.